amp2response

Synopsis

Estimate response function coefficients based on the DWI signal in single-fibre voxels

Usage

amp2response [ options ]  amps mask directions response
  • amps: the amplitudes image
  • mask: the mask containing the voxels from which to estimate the response function
  • directions: a 4D image containing the estimated fibre directions
  • response: the output zonal spherical harmonic coefficients

Description

This command uses the image data from all selected single-fibre voxels concurrently, rather than simply averaging their individual spherical harmonic coefficients. It also ensures that the response function is non-negative, and monotonic (i.e. its amplitude must increase from the fibre direction out to the orthogonal plane).

If multi-shell data are provided, and one or more b-value shells are not explicitly requested, the command will generate a response function for every b-value shell (including b=0 if present).

Options

  • -isotropic estimate an isotropic response function (lmax=0 for all shells)
  • -noconstraint disable the non-negativity and monotonicity constraints
  • -directions path provide an external text file containing the directions along which the amplitudes are sampled

DW shell selection options

  • -shells b-values specify one or more b-values to use during processing, as a comma-separated list of the desired approximate b-values (b-values are clustered to allow for small deviations). Note that some commands are incompatible with multiple b-values, and will report an error if more than one b-value is provided. WARNING: note that, even though the b=0 volumes are never referred to as shells in the literature, they still have to be explicitly included in the list of b-values as provided to the -shell option! Several algorithms which include the b=0 volumes in their computations may otherwise return an undesired result.
  • -lmax values specify the maximum harmonic degree of the response function to estimate (can be a comma-separated list for multi-shell data)

Standard options

  • -info display information messages.
  • -quiet do not display information messages or progress status; alternatively, this can be achieved by setting the MRTRIX_QUIET environment variable to a non-empty string.
  • -debug display debugging messages.
  • -force force overwrite of output files (caution: using the same file as input and output might cause unexpected behaviour).
  • -nthreads number use this number of threads in multi-threaded applications (set to 0 to disable multi-threading).
  • -config key value (multiple uses permitted) temporarily set the value of an MRtrix config file entry.
  • -help display this information page and exit.
  • -version display version information and exit.

References

Smith, R. E.; Dhollander, T. & Connelly, A. Constrained linear least squares estimation of anisotropic response function for spherical deconvolution. ISMRM Workshop on Breaking the Barriers of Diffusion MRI, 23.


Author: Robert E. Smith (robert.smith@florey.edu.au) and J-Donald Tournier (jdtournier@gmail.com)

Copyright: Copyright (c) 2008-2019 the MRtrix3 contributors.

This Source Code Form is subject to the terms of the Mozilla Public License, v. 2.0. If a copy of the MPL was not distributed with this file, You can obtain one at http://mozilla.org/MPL/2.0/.

Covered Software is provided under this License on an “as is” basis, without warranty of any kind, either expressed, implied, or statutory, including, without limitation, warranties that the Covered Software is free of defects, merchantable, fit for a particular purpose or non-infringing. See the Mozilla Public License v. 2.0 for more details.

For more details, see http://www.mrtrix.org/.