Calculate the mean response function from a set of text files


responsemean inputs output [ options ]
  • inputs: The input response functions
  • output: The output mean response function


Example usage: responsemean input_response1.txt input_response2.txt input_response3.txt … output_average_response.txt

All response function files provided must contain the same number of unique b-values (lines), as well as the same number of coefficients per line.

As long as the number of unique b-values is identical across all input files, the coefficients will be averaged. This is performed on the assumption that the actual acquired b-values are identical. This is however impossible for the responsemean command to determine based on the data provided; it is therefore up to the user to ensure that this requirement is satisfied.


  • -legacy Use the legacy behaviour of former command ‘average_response’: average response function coefficients directly, without compensating for global magnitude differences between input files

Additional standard options for Python scripts

  • -nocleanup do not delete intermediate files during script execution, and do not delete scratch directory at script completion.
  • -scratch /path/to/scratch/ manually specify the path in which to generate the scratch directory.
  • -continue <ScratchDir> <LastFile> continue the script from a previous execution; must provide the scratch directory path, and the name of the last successfully-generated file.

Standard options

  • -info display information messages.
  • -quiet do not display information messages or progress status. Alternatively, this can be achieved by setting the MRTRIX_QUIET environment variable to a non-empty string.
  • -debug display debugging messages.
  • -force force overwrite of output files.
  • -nthreads number use this number of threads in multi-threaded applications (set to 0 to disable multi-threading).
  • -config key value (multiple uses permitted) temporarily set the value of an MRtrix config file entry.
  • -help display this information page and exit.
  • -version display version information and exit.


Tournier, J.-D.; Smith, R. E.; Raffelt, D.; Tabbara, R.; Dhollander, T.; Pietsch, M.; Christiaens, D.; Jeurissen, B.; Yeh, C.-H. & Connelly, A. MRtrix3: A fast, flexible and open software framework for medical image processing and visualisation. NeuroImage, 2019, 202, 116137

Author: Robert E. Smith ( and David Raffelt (

Copyright: Copyright (c) 2008-2020 the MRtrix3 contributors.

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